April 10, 2026 · Dr. Okezie Emmanuel

Biomanufacturing for a Net-Zero Carbon Future: Strategies That Actually Scale

Our new review in Bioresource Technology Reports maps how microbial innovation and biomanufacturing can deliver on net-zero commitments.

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Biomanufacturing for a Net-Zero Carbon Future: Strategies That Actually Scale

Beyond the Buzzword

"Net-zero" appears in corporate sustainability reports, national climate pledges, and university strategic plans — but what does it actually require at the level of industrial chemical production? Our 2026 review in Bioresource Technology Reports"Harnessing biomanufacturing and microbial innovation for a sustainable and net-zero carbon future" — co-authored with Nasib Qureshi, Teddy Ezeji, and John Hallsworth, tackles this question directly.

Three Pillars of Net-Zero Biomanufacturing

The review identifies three interconnected strategies that must work together:

  1. Feedstock diversification — shifting from food crops to lignocellulosic biomass, food wastes, and non-edible seed oils as fermentation substrates
  2. Microbial platform engineering — metabolic and process engineering of solventogenic Clostridium, yeast, and bacterial cell factories
  3. Process integration — coupling fermentation with in-situ product recovery (gas stripping, pervaporation) and waste-derived catalyst systems

From Laboratory to Policy

What makes this review distinct is its emphasis on synergies — not just listing technologies but showing how they connect. Biomass valorization feeds microbial fermentation; fermentation produces CO₂ that can be captured and converted; waste streams become catalyst precursors. This circular logic is the foundation of a genuinely net-zero biomanufacturing economy.

My NSF Research Traineeship in Sustainable Energy and the 2024 Sustainability Institute Student Grant ($5,000) provided the interdisciplinary framework for this work, connecting microbiology, chemical engineering, and environmental policy perspectives.

A Personal Reflection

Writing this review while completing my Ph.D. dissertation crystallized something I had felt intuitively for years: the research I began in Nigeria on plant biochemistry and the fermentation engineering I do in Ohio are part of the same sustainability equation. Both ask how we use biological systems to meet human needs without destroying the ecosystems that sustain us.

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Dr. Okezie Emmanuel

Graduate Fellow · Department of Animal Sciences · The Ohio State University

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